化工社化工社 化学情報印刷レポート · 研究参考用
1,4-Dioxane hydrochloride → 2-Aminoindan-5-carboxylic acid morpholinamide hydrochloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1,4-Dioxane hydrochloride | HCID 20443148 | — |
| 反応物 | 2-(Tert-butoxycarbonylamino)indan-5-carboxylic acid morpholinamide | HCID 131724366 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 生成物 | 2-Aminoindan-5-carboxylic acid morpholinamide hydrochloride | HCID 69849846 | — |
反応手順
Using 2-(tert-butoxycarbonylamino)indan-5-carboxylic acid morpholinamide (1.0 g, 2.7 mmol), 4N hydrochloric acid-dioxane (12 ml) and acetic acid (36 ml), a similar procedure to Production Example 213 was carried out to obtain 2-aminoindan-5-carboxylic acid morpholinamide hydrochloride (750 mg, 2.7 mmol) having the following physical properties:
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06703421B1 |
| 出典データセット | uspto-grants-2004_03 |
| ORD ID | ord-fa21e3f9e6904a029afbc3594e1dbb39 |
| 出典メモ | uspto-grants-2004_03 |