化工社化工社 化学情報印刷レポート · 研究参考用
Sodium Iodide → Methyl 4-(tetradecyloxy)benzoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sodium Iodide | HCID 5238 | — |
| 反応物 | Methylparaben | HCID 7456 | — |
| 反応物 | Myristyl bromide | HCID 8208 | — |
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 溶媒 | Acetone | HCID 180 | — |
| 生成物 | Methyl 4-(tetradecyloxy)benzoate | HCID 3312490 | 8.1% |
反応手順
A well stirred mixture of 100 g of methyl 4-hydroxybenzoate, 182.25 g of tetradecylbromide, 136.26 g of potassium carbonate and 4.93 g of sodium iodide in 1-liter of acetone is refluxed for 48 hours. The mixture is poured into ice water, the solid collected and washed with water. The solid is dissolved in chloroform and washed with 1N sodium hydroxide, dried and evaporated to a residue which is crystallized from hexanes to give 18.5 g of the desired product as a white solid, m.p. 64°-66° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05231182 |
| 出典データセット | uspto-grants-1993_07 |
| ORD ID | ord-a012738f83fa4824a423cb5d3cec533b |
| 出典メモ | uspto-grants-1993_07 |