Hydrochloric Acid → HCID 20135909、化合物

HRID 484895ノート

反応式

HRID 484895 の反応式
[CH2:1]([N:3]([CH2:26][CH3:27])[CH2:4][CH2:5][CH2:6][N:7]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][C:14]=2[I:16])[C:9]([NH:17][CH2:18][CH2:19][CH2:20][N:21]([CH2:24][CH3:25])[CH2:22][CH3:23])=[N:8]1)[CH3:2].[ClH:28].C(OCC)C>C(O)C>[ClH:28].[ClH:28].[CH2:26]([N:3]([CH2:1][CH3:2])[CH2:4][CH2:5][CH2:6][N:7]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][C:14]=2[I:16])[C:9]([NH:17][CH2:18][CH2:19][CH2:20][N:21]([CH2:22][CH3:23])[CH2:24][CH3:25])=[N:8]1)[CH3:27]

参加物

5

反応物 3

HCID 313Hydrochloric AcidHCID 3283Diethyl EtherHCID 20135888HCID 20135888、化合物

生成物 1

HCID 20135909HCID 20135909、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

In 50 ml of absolute ethyl alcohol was dissolved 4.0 g of the 1-(3-diethylaminopropyl)-3-(3-diethylaminopropylamino)-7-iodoindazole, and into the solution was introduced dried hydrogen chloride gas under cooling with ice. Then to the solution was added anhydrous diethyl ether to separate crystals. The crystals were obtained by filtration and dried to give 1-(3-diethylaminopropyl)-3-(3-diethylaminopropylamino)-7-iodoindazole dihydrochloride having the following analytical value.

後処理

  1. temperatureunder cooling with ice
  2. customto separate crystals
  3. customThe crystals were obtained by filtration
  4. customdried

出典と根拠

ORDレコード
ord-8b17a9ebab4040a0817223b23cc72d9f
出典データセット
uspto-grants-1985_08
特許番号
US04533731

反応ノート

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