1,8-Octanediamine, 4-(aminomethyl)- → 1,8-Bis(N-[2,4-bis(2,2,6,6-tetramethylpiperid-4-ylamino)-1,3,5-triazin-6-yl]amino)-4-(N-[2,4-bis(2,2,6,6-tetramethylpiperid-4-ylamino)-1,3,5-triazin-6-yl]aminomethyl)octane

HRID 484947ノート

反応式

HRID 484947 の反応式
Cl[C:2]1[N:7]=[C:6]([NH:8][CH:9]2[CH2:14][C:13]([CH3:16])([CH3:15])[NH:12][C:11]([CH3:18])([CH3:17])[CH2:10]2)[N:5]=[C:4]([NH:19][CH:20]2[CH2:25][C:24]([CH3:27])([CH3:26])[NH:23][C:22]([CH3:29])([CH3:28])[CH2:21]2)[N:3]=1.[NH2:30][CH2:31][CH2:32][CH2:33][CH:34]([CH2:40][NH2:41])[CH2:35][CH2:36][CH2:37][CH2:38][NH2:39]>O>[CH3:28][C:22]1([CH3:29])[CH2:21][CH:20]([NH:19][C:4]2[N:5]=[C:6]([NH:8][CH:9]3[CH2:14][C:13]([CH3:16])([CH3:15])[NH:12][C:11]([CH3:18])([CH3:17])[CH2:10]3)[N:7]=[C:2]([NH:30][CH2:31][CH2:32][CH2:33][CH:34]([CH2:40][NH:41][C:2]3[N:7]=[C:6]([NH:8][CH:9]4[CH2:14][C:13]([CH3:16])([CH3:15])[NH:12][C:11]([CH3:17])([CH3:18])[CH2:10]4)[N:5]=[C:4]([NH:19][CH:20]4[CH2:25][C:24]([CH3:26])([CH3:27])[NH:23][C:22]([CH3:28])([CH3:29])[CH2:21]4)[N:3]=3)[CH2:35][CH2:36][CH2:37][CH2:38][NH:39][C:2]3[N:3]=[C:4]([NH:19][CH:20]4[CH2:25][C:24]([CH3:27])([CH3:26])[NH:23][C:22]([CH3:29])([CH3:28])[CH2:21]4)[N:5]=[C:6]([NH:8][CH:9]4[CH2:10][C:11]([CH3:18])([CH3:17])[NH:12][C:13]([CH3:16])([CH3:15])[CH2:14]4)[N:7]=3)[N:3]=2)[CH2:25][C:24]([CH3:27])([CH3:26])[NH:23]1

参加物

4

反応物 2

HCID 942111,8-Octanediamine, 4-(aminomethyl)-HCID 214680172-Chloro-4,6-bis(2,2,6,6-tetramethyl-4-piperidylamino)-1,3,5-triazine

生成物 1

HCID 202721371,8-Bis(N-[2,4-bis(2,2,6,6-tetramethylpiperid-4-ylamino)-1,3,5-triazin-6-yl]amino)-4-(N-[2,4-bis(2,2,6,6-tetramethylpiperid-4-ylamino)-1,3,5-triazin-6-yl]aminomethyl)octane

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

5.1 g of 2-chloro-4,6-bis[N-(2,2,6,6-tetramethyl-4-piperidyl)amino]-1,3,5-triazine [prepared as described in Preparation 9(b)] were reacted with 0.7 g of 1,8-diamino-4-aminomethyloctane, following the procedure described in Example 9. After completion of the reaction, the reaction mixture was poured into water and extracted with chloroform. The extract was dried over anhydrous potassium carbonate, and the solvent was distilled off. The residue was purified by column chromatography through silica gel, eluted with a 8:2:1 by volume mixture of ethyl acetate, ethanol and triethylamine, to give the desired Compound No. 1 in the form of crystals melting at 148°-158° C.

後処理

  1. customAfter completion of the reaction
  2. extractionextracted with chloroform
  3. dry with materialThe extract was dried over anhydrous potassium carbonate
  4. distillationthe solvent was distilled off
  5. customThe residue was purified by column chromatography through silica gel
  6. washeluted with a 8:2:1 by volume mixture of ethyl acetate, ethanol and triethylamine

出典と根拠

ORDレコード
ord-1ea1e17b3bb245cf80c2b46ec1cd01fe
出典データセット
uspto-grants-1985_08
特許番号
US04533688

反応ノート

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