Methanol → Methyl 2-bromo-4-methylpentanoate
反応式
[Br:1][CH:2]([CH2:6][CH:7]([CH3:9])[CH3:8])[C:3](Cl)=[O:4].[CH3:10][OH:11]>>[CH3:10][O:11][C:3](=[O:4])[CH:2]([Br:1])[CH2:6][CH:7]([CH3:9])[CH3:8]参加物
3
実験手順
2-Bromo-4-methylpentanoyl chloride (IV, Example 2) is added dropwise to methyl alcohol (200 ml.) at 0°. After two hours the methanol is removed under reduce pressure and the residual oil is partitioned between chloroform and water. The chloroform is separated from the water and removed under reduced pressure to give a residual oil which is distilled under reduced pressure to give the title compound, b.p. 78°-90°/30 mm.
後処理
- customAfter two hours the methanol is removed
- customthe residual oil is partitioned between chloroform and water
- customThe chloroform is separated from the water
- customremoved under reduced pressure
- customto give a residual oil which
- distillationis distilled under reduced pressure
出典と根拠
- ORDレコード
- ord-ef708403d1f1434c8a3eed888161b871
- 出典データセット
- uspto-grants-1985_08
- 特許番号
- US04534897
反応ノート
読み込み中…