Methanol → 2-(2-Phenyl-5-isopropyl-4-oxazolyl)acetic acid
反応式
[C:1]1([C:7]2[O:8][C:9]([CH:18]([CH3:20])[CH3:19])=[C:10]([CH2:12][C:13]([O:15]CC)=[O:14])[N:11]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.CO.[OH-].[K+]>O>[C:1]1([C:7]2[O:8][C:9]([CH:18]([CH3:20])[CH3:19])=[C:10]([CH2:12][C:13]([OH:15])=[O:14])[N:11]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1参加物
5
実験手順
2.73 g of ethyl 2-(2-phenyl-5-isopropyl-4-oxazolyl)acetate, 20 ml of methanol, 5 ml of water and 1.1 g of potassium hydroxide are treated in the same manner as described in Example 8. 2.39 g of 2-(2-phenyl-5-isopropyl-4-oxazolyl)acetic acid are thereby obtained. Yield: 97.4%.
出典と根拠
- ORDレコード
- ord-b204aa53965e4d9fb3ccb7c43ef0fd10
- 出典データセット
- uspto-grants-1985_08
- 特許番号
- US04535089
反応ノート
読み込み中…