Sodium Acetate → 2-Methyl-4-oxo-3-(prop-2-en-1-yl)cyclopent-2-en-1-yl acetate

HRID 485123ノート

反応式

HRID 485123 の反応式
[CH2:1]([CH:4]1[C:8](O)([CH3:9])[CH:7]=[CH:6][C:5]1=[O:11])[CH:2]=[CH2:3].[C:12]([O-:15])(=[O:14])[CH3:13].[Na+]>C(O)(=O)C>[C:12]([O:15][CH:7]1[CH2:6][C:5](=[O:11])[C:4]([CH2:1][CH:2]=[CH2:3])=[C:8]1[CH3:9])(=[O:14])[CH3:13]

参加物

4

反応物 2

HCID 517045Sodium AcetateHCID 128798724-Hydroxy-4-methyl-5-(prop-2-en-1-yl)cyclopent-2-en-1-one

生成物 1

HCID 131027602-Methyl-4-oxo-3-(prop-2-en-1-yl)cyclopent-2-en-1-yl acetate収率 390.7%

試薬・触媒・溶媒 1

HCID 176Acetic Acid溶媒2 回

実験手順

In the same apparatus as in Example 1, 2-allyl-3-hydroxy-3-methyl-4-cyclopentenone (15.2 g), acetic acid (45 ml) and sodium acetate (2 g) were charged and heated to reflux for 7 hours. After the completion of the reaction, acetic acid was evaporated off under reduced pressure. The residue was extracted with toluene (60 ml) and water (40 ml) and treated as in Example 1 to obtain 4-acetoxy-2-allyl-3-methyl-2-cyclopentenone (18.5 g). Yield, 95.3%. B.P., 100°-110° C./0.1-0.3 mmHg.

後処理

  1. temperatureheated
  2. temperatureto reflux for 7 hours
  3. customwas evaporated off under reduced pressure
  4. extractionThe residue was extracted with toluene (60 ml) and water (40 ml)
  5. additiontreated as in Example 1

出典と根拠

ORDレコード
ord-b15c076b8b4a46448ada65822b435708
出典データセット
uspto-grants-1985_08
特許番号
US04535182

反応ノート

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