関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Acetone | HCID 180 | — |
| 反応物 | 1,4-Dimethylpiperazine | HCID 7818 | — |
| 反応物 | 2-Bromoethyl thiolacetate | HCID 57091359 | — |
| 生成物 | 1-[2-(Acetylsulfanyl)ethyl]-1,4-dimethylpiperazin-1-ium bromide | HCID 20203366 | — |
反応手順
A solution of 2-bromoethyl thiolacetate *(2.20 g, 0.012 mol) and 1,4-dimethylpiperazine (1.95 mL, 0.014 mol) in acetone (4 mL) was stirred at 50° C. for 65 h. After cooling to 25° C., the liquid phase was decanted from the gum which was triturated twice in diethyl ether; a hygroscopic yellowish powder, 3.2 g (90%) was obtained; ir (Nujol) νmax : 1685 (C=O of thioester) cm-1 ; 1Hmr (D2O) δ: 2.37, 2.39 ##STR122##
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04536335 |
|---|
| 出典データセット | uspto-grants-1985_08 |
|---|
| ORD ID | ord-71534d3bdf0f4eb3a161bb0157aa94b6 |
|---|
| 出典メモ | uspto-grants-1985_08 |
|---|
