Methylamine → 3-(2'-chloro-4'-trifluoromethylphenoxy)-6-nitrobenzene N-methylsulfenamide

HRID 485620ノート

反応式

HRID 485620 の反応式
[CH3:1][NH2:2].[Cl:3][C:4]1[CH:21]=[C:20]([C:22]([F:25])([F:24])[F:23])[CH:19]=[CH:18][C:5]=1[O:6][C:7]1[CH:8]=[C:9]([S:16]Cl)[C:10]([N+:13]([O-:15])=[O:14])=[CH:11][CH:12]=1>CCOCC>[Cl:3][C:4]1[CH:21]=[C:20]([C:22]([F:23])([F:25])[F:24])[CH:19]=[CH:18][C:5]=1[O:6][C:7]1[CH:8]=[CH:9][C:10]([N+:13]([O-:15])=[O:14])=[CH:11][CH:12]=1.[CH3:1][NH:2][SH:16]

参加物

4

反応物 2

HCID 6329MethylamineHCID 13246608HCID 13246608、化合物

生成物 1

HCID 867402683-(2'-chloro-4'-trifluoromethylphenoxy)-6-nitrobenzene N-methylsulfenamide収率 95%

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒

実験手順

3.1 g of methylamine in the form of a 40% strength aqueous solution were added to a solution of 19.2 parts by weight of 3-(2'-chloro-4'-trifluoromethylphenoxy)-6-nitrobenzenesulfenyl chloride in 100 parts by volume of ether, and stirring was continued for a further 2 hours at room temperature. The organic phase was separated off, dried with magnesium sulfate, filtered, and evaporated down under reduced pressure. 17.5 parts by weight (95% yield) of 3-(2'-chloro-4'-trifluoromethylphenoxy)-6-nitrobenzene-N-methylsulfenamide of refractive index nD25 : 1.6109 were obtained (compound No. 5).

後処理

  1. customThe organic phase was separated off
  2. dry with materialdried with magnesium sulfate
  3. filtrationfiltered
  4. customevaporated down under reduced pressure

出典と根拠

ORDレコード
ord-92db66c6937445a49868ecfa2e625f80
出典データセット
uspto-grants-1985_08
特許番号
US04537621

反応ノート

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