N-Methylisatoic anhydride → HCID 178482128、化合物

反応式

[NH:1]1[C:9]2[C:4](=[N:5][CH:6]=[CH:7][CH:8]=2)[C:3](=[O:10])[NH:2]1.[CH3:11][N:12]1C(=O)O[C:15](=[O:16])[C:14]2=[CH:20][CH:21]=[CH:22][CH:23]=[C:13]12>>[OH:10][C:3]1[C:4]2=[N:5][CH:6]=[CH:7][CH:8]=[C:9]2[N:1]([C:15](=[O:16])[C:14]2[CH:20]=[CH:21][CH:22]=[CH:23][C:13]=2[NH:12][CH3:11])[N:2]=1

参加物

反応物 2

HCID 25160N-Methylisatoic anhydride

HCID 122133831,2-Dihydro-3H-pyrazolo[4,3-b]pyridin-3-one

生成物 1

HCID 178482128HCID 178482128、化合物収率 84.8%

実験手順

Pyrazolo[4,3-b]pyridine-3(2H)-one was reacted with N-methylisatoic anhydride according to the general procedure A above and afforded the desired amine as a yellow solid in 84.8% yield; m.p. 221°-223° C.,

出典と根拠

ORDレコード: ord-3ec681c2510d4e32a4503548d2c8e53e
出典データセット: uspto-grants-1985_08
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04537966

反応ノート

読み込み中…