1-Decanethiol → HCID 178443463、化合物

HRID 485971ノート

反応式

HRID 485971 の反応式
[OH:1][CH2:2][CH2:3][N:4]=[C:5]([OH:33])[C:6]1[C:7](=[C:11](Cl)[C:12]([S:24][C:25]2[CH:30]=[CH:29][C:28]([CH3:31])=[CH:27][CH:26]=2)=[C:13]([S:16][C:17]2[CH:22]=[CH:21][C:20]([CH3:23])=[CH:19][CH:18]=2)[C:14]=1Cl)[C:8]([OH:10])=[O:9].[CH2:34]([SH:44])[CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH3:43].C(=O)([O-])[O-].[K+].[K+]>CN(C)C=O>[OH:1][CH2:2][CH2:3][N:4]=[C:5]([OH:33])[C:6]1[C:7](=[C:11]([S:44][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH3:43])[C:12]([S:24][C:25]2[CH:30]=[CH:29][C:28]([CH3:31])=[CH:27][CH:26]=2)=[C:13]([S:16][C:17]2[CH:22]=[CH:21][C:20]([CH3:23])=[CH:19][CH:18]=2)[C:14]=1[S:44][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH3:43])[C:8]([OH:10])=[O:9]

参加物

5

反応物 3

HCID 89171-DecanethiolHCID 11430Potassium CarbonateHCID 178427278HCID 178427278、化合物

生成物 1

HCID 178443463HCID 178443463、化合物

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

実験手順

2 g (3.95 millimols) of 4,5-bis-(p-tolylthio)-3,6-dichlorophthalic acid N-2-hydroxyethylimide, 1,51 g (8.69 millimols) of n-decane-1-thiol, 2.29 g (16.58 millimols) of potassium carbonate and 20 ml of N,N-dimethylformamide are stirred at 25° C. for 1 hour. After concentration, the residue is taken up in methylene chloride/dilute HCl solution. The extracts are dried over sodium sulfate and evaporated. After precipitation from n-hexane, 300 mg (10% of theory) of the title compound (waxy substance) are obtained.

後処理

  1. concentrationAfter concentration
  2. dry with materialThe extracts are dried over sodium sulfate
  3. customevaporated
  4. customAfter precipitation from n-hexane, 300 mg (10% of theory) of the title compound (waxy substance)
  5. customare obtained

出典と根拠

ORDレコード
ord-1302995189ae4247b2f82eaa3f97a735
出典データセット
uspto-grants-1985_08
特許番号
US04537977

反応ノート

読み込み中…