1-((2-Chloroethyl)thio)hexane → HCID 178445572、化合物

反応式

[NH2:1][C:2]1[N:6]=[C:5]([S:7][CH2:8][CH2:9][S:10][CH2:11][CH2:12]SCCCCCC)[NH:4][N:3]=1.[CH2:20](SCCCl)[CH2:21][CH2:22][CH2:23]CC>>[NH2:1][C:2]1[N:6]=[C:5]([S:7][CH2:8][CH2:9][S:10][CH2:11][CH2:12][CH2:20][CH2:21][CH2:22][CH3:23])[NH:4][N:3]=1

参加物

反応物 2

HCID 122602791-((2-Chloroethyl)thio)hexane

HCID 1784455743-Amino-5-{2-[2-(hexylthio)ethylthio]ethylthio}-1,2,4-triazole

生成物 1

HCID 178445572HCID 178445572、化合物収率 86%

実験手順

Compound 6 was prepared using the procedure used for Compound 12, but with 2-chloroethyl hexyl sulfide as the starting material. The yield was 86%. A portion was recrystallized from ligroin/ethyl acetate to obtain a solid, m.p. 76.5°-78° C. Analysis: Calculated for C10H20N4S2 : C, 46.12; H, 7.74; N, 21.51. Found: C, 46.00; H, 7.56; N, 21.56.

後処理

customA portion was recrystallized from ligroin/ethyl acetate
customto obtain a solid, m.p. 76.5°-78° C

出典と根拠

ORDレコード: ord-046e7a63452d490ab3f392038e3f1525
出典データセット: uspto-grants-1994_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05292627

反応ノート

読み込み中…

参加物