Lithium Chloride → Cyclopentanone, 2-(2-methyl-2-propenyl)-
反応式
COC([C:5]1([CH2:11][C:12]([CH3:14])=[CH2:13])[CH2:9][CH2:8][CH2:7][C:6]1=[O:10])=O.[Li+].[Cl-]>CN(P(N(C)C)(N(C)C)=O)C>[CH3:14][C:12](=[CH2:13])[CH2:11][CH:5]1[CH2:9][CH2:8][CH2:7][C:6]1=[O:10]参加物
4
反応条件
- 温度
- 73 °C
実験手順
A mixture of methyl-1-(2-methyl-2-propenyl)-2-oxo-1-cyclopentanecarboxylate (78.4 g), HMPA (hexamethylphosphoramide, 250 ml) and LiCl (34 g) is heated to 73° C. for 36 hrs. Extraction (3 times, ether/water) of the reaction product provides a brown oil which, upon fractional distillation (63° C.-75° C./5.32×102Pa), yields 2-(2-methyl-2-propenyl)-1-cyclopentanone.
後処理
- extractionExtraction (3 times, ether/water) of the reaction product
- customprovides a brown oil which
- distillationupon fractional distillation (63° C.-75° C./5.32×102Pa)
出典と根拠
- ORDレコード
- ord-9c32e307e20b402b87209b0f4dc12dd7
- 出典データセット
- uspto-grants-1994_03
- 特許番号
- US05292719
反応ノート
読み込み中…