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Sulfuric Acid → 3,3,4,4,5,5,5-Heptafluoro-2-methylpentan-2-ol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sulfuric Acid | HCID 1118 | — |
| 反応物 | Methyl 2,2,3,3,4,4,4-heptafluorobutanoate | HCID 67741 | — |
| 反応物 | 2-Methyl-3,3,4,4,5,5,5-heptafluoro-pent-1-ene | HCID 19091131 | — |
| 触媒 | Rhodium | HCID 23948 | — |
| 生成物 | 3,3,4,4,5,5,5-Heptafluoro-2-methylpentan-2-ol | HCID 540479 | — |
| 生成物 | 2-Methyl-3,3,4,4,5,5,5-heptafluoropentane | HCID 19091139 | — |
反応手順
Following the procedure of E. T. McBee et al. ibid, 2-methyl-3,3,4,4,5,5,5-heptafluoro-pentan-2-ol was prepared by adding methyl heptafluorobutyrate to 2 equivalents of methyl Grignard. The alcohol (boiling point 108° C.) was dehydrated with concentrated sulfuric acid to 2-methyl-3,3,4,4,5,5,5-heptafluoro-pent-1-ene (boiling point 55° C.). Hydrogenation of this olefin at 1500 psig using 5% rhodium/carbon gave 2-methyl-3,3,4,4,5,5,5-heptafluoropentane, boiling point 59°-61° C. 1H NMR (CDCl3)δ 1.2 (d, 6 Hz), 2.45 (m). This compound was miscible with silicone oil with a perfluorinated polyether at 25° C. and with light mineral oil at 56° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05298083 |
| 出典データセット | uspto-grants-1994_03 |
| ORD ID | ord-eb7b9f58b1a643fc86084c6992c7e191 |
| 出典メモ | uspto-grants-1994_03 |