N-(3-ethynylphenyl)acetamide → 2-(3-Acetylamino-phenylethynyl)-3,5-dimethyl-3H-imidazole-4-carboxylic acid ethyl ester

HRID 488467

反応式

HRID 488467 の反応式
[C:1]([C:3]1[CH:4]=[C:5]([NH:9][C:10](=[O:12])[CH3:11])[CH:6]=[CH:7][CH:8]=1)#[CH:2].[CH2:13]([O:15][C:16]([C:18]1[N:19]([CH3:25])[C:20](Br)=[N:21][C:22]=1[CH3:23])=[O:17])[CH3:14]>>[CH2:13]([O:15][C:16]([C:18]1[N:19]([CH3:25])[C:20]([C:2]#[C:1][C:3]2[CH:8]=[CH:7][CH:6]=[C:5]([NH:9][C:10](=[O:12])[CH3:11])[CH:4]=2)=[N:21][C:22]=1[CH3:23])=[O:17])[CH3:14]

参加物

3

反応物 2

HCID 2726447N-(3-ethynylphenyl)acetamideHCID 13897513ethyl 2-bromo-1,4-dimethyl-1H-imidazole-5-carboxylate

生成物 1

HCID 102681942-(3-Acetylamino-phenylethynyl)-3,5-dimethyl-3H-imidazole-4-carboxylic acid ethyl ester

実験手順

The title compound, MS: m/e=326.8 (M+H+), was prepared in accordance with the general method of example 1b from N-(3-ethynyl-phenyl)-acetamide and 2-bromo-3,5-dimethyl-3H-imidazole-4-carboxylic acid ethyl ester.

出典と根拠

ORDレコード
ord-5d7fdcec14f54bf692b945ee61aee2e2
出典データセット
uspto-grants-2005_12
特許番号
US06972299B2

関連ノート

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