化工社化工社 化学情報印刷レポート · 研究参考用
Hydrochloric Acid → Methyl 3-(4-aminobutoxy)-1-hydroxy-2-naphthoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Methyl 3-{4-[(tert-butoxycarbonyl)amino]butoxy}-1-(methoxymethoxy)-2-naphthoate | HCID 22271972 | — |
| 溶媒 | 1,4-Dioxane | HCID 31275 | — |
| 生成物 | Methyl 3-(4-aminobutoxy)-1-hydroxy-2-naphthoate | HCID 22271969 | 102.6% |
反応手順
To a mixture of methyl 3-{4-[(tert-butoxycarbonyl)amino]butoxy}-1-(methoxymethoxy)-2-naphthoate (28 mg, 0.064 mmol) was added 4M HCl in dioxane (1 mL). The mixture was stirred at ambient temperature for 30 minutes, concentrated under reduced pressure to provide the titled compound (19 mg, 100%) as its hydrochloride salt.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06972340B2 |
| 出典データセット | uspto-grants-2005_12 |
| ORD ID | ord-5eae51615e85413895203e397774bdcf |
| 出典メモ | uspto-grants-2005_12 |