Bromine → 2-Bromo-1,3-diphenyl-1-propanone

HRID 488770

反応式

HRID 488770 の反応式
[C:1]1([C:7](=[O:16])[CH2:8][CH2:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Br:17]Br>O1CCOCC1>[Br:17][CH:8]([CH2:9][C:10]1[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=1)[C:7]([C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)=[O:16]

参加物

4

反応物 2

HCID 24408BromineHCID 64802Dihydrochalcone2 回

生成物 1

HCID 30396872-Bromo-1,3-diphenyl-1-propanone

試薬・触媒・溶媒 1

HCID 312751,4-Dioxane溶媒2 回

実験手順

To a solution of 1,3-diphenylpropan-1-one (compound 2) (7.0 mmol) in 25 ml of anhydrous dioxane, a solution of bromine (7.0 mmol) in 10 ml of dioxane was slowly added dropwise over 30 min. The reaction mixture was left to stir at room temperature for 24 hrs to form 2-bromo-1,3-diphenylpropan-1-one (compound 3). Solvent was removed in vacuo. The 2-bromo-1,3-diphenylpropan-1-one product formed was determined by 1H NMR to be sufficiently pure to be used in the next step.

後処理

  1. waitThe reaction mixture was left

出典と根拠

ORDレコード
ord-7893031004964d65825ebce55d7a7866
出典データセット
uspto-grants-2005_12
特許番号
US06974830B2

関連ノート

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