(Ethoxy-phenyl-phosphinoyl)-hydroxy-acetic acid ethyl ester → Hydroxy-(hydroxy-phenyl-phosphinoyl)-acetic acid
反応式
C([O:3][C:4](=[O:18])[CH:5]([P:7]([O:15]CC)([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)=[O:8])[OH:6])C>Cl>[OH:6][CH:5]([P:7]([OH:15])([C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=1)=[O:8])[C:4]([OH:18])=[O:3]参加物
3
実験手順
To a solution of (ethoxy-phenyl-phosphinoyl)-hydroxy-acetic acid ethyl ester (382 mg, 1.41 mmol) in 10 mL of 6 M HCl was heated to reflux overnight. The resulting mixture was concentrated to a minimum volume and lyophilized affording a pale yellow solid (274 mg, 90%)
後処理
- temperatureto reflux overnight
- concentrationThe resulting mixture was concentrated to a minimum volume
出典と根拠
- ORDレコード
- ord-813ab4ec9a4442d3b025a4b348af6c3e
- 出典データセット
- uspto-grants-2004_03
- 特許番号
- US06706699B2
反応ノート
読み込み中…