6-Bromohexanoic acid → HCID 178433620、化合物
反応式
[CH3:1][C:2]1[C:3]([CH3:12])([CH3:11])[C:4]2[C:5]([N:10]=1)=[N:6][CH:7]=[CH:8][CH:9]=2.[Br:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][C:19]([OH:21])=[O:20]>C(OCC)(=O)C>[Br-:13].[C:19]([CH2:18][CH2:17][CH2:16][CH2:15][CH2:14][N:6]1[CH:7]=[CH:8][CH:9]=[C:4]2[C:3]([CH3:12])([CH3:11])[CH:2]([CH3:1])[NH+:10]=[C:5]12)([OH:21])=[O:20]参加物
4
反応条件
- 温度
- 120 °C
実験手順
A mixture of 0.54 g of 2,3,3-trimethyl-3H-pyrrolo[2,3-b]pyridine and 1.32 g of 6-bromohexanoic acid is heated at 120° C. for one hour. Ethyl acetate (10 mL) is added, and the reaction mixture is heated at reflux for 15 minutes, then cooled to room temperature. The supernatant liquid is decanted to yield the product.
後処理
- temperaturethe reaction mixture is heated
- temperatureat reflux for 15 minutes
- temperaturecooled to room temperature
- customThe supernatant liquid is decanted
- customto yield the product
出典と根拠
- ORDレコード
- ord-66aa759ffdb4428ba4d5cbcfbc88271b
- 出典データセット
- uspto-grants-2005_12
- 特許番号
- US06977305B2
反応ノート
読み込み中…