(S)-N-Benzyl-2-(Boc-amino)-2-phenylacetamide → (S)-2-Amino-N-benzyl-2-phenyl-acetamide hydrochloride
反応式
C(OC(=O)[NH:7][C@H:8]([C:15](=[O:24])[NH:16][CH2:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)(C)(C)C.[ClH:26].O1CCOCC1>>[ClH:26].[NH2:7][C@@H:8]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[C:15]([NH:16][CH2:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)=[O:24]参加物
3
実験手順
(S)-(Benzylcarbamoyl-phenyl-methyl)-carbamic acid tert-butyl ester (0.85 g, 2.50 mmol) was dissolved in HCl/dioxane(10 mL, 4.0 M). The mixture was stirred at room temperature overnight. The volatiles were removed under reduced pressure to provide the desired product in quantitative yield.
後処理
- customThe volatiles were removed under reduced pressure
出典と根拠
- ORDレコード
- ord-45243f1e84b54dee9a6a87609a732368
- 出典データセット
- uspto-grants-2005_12
- 特許番号
- US06979692B2
反応ノート
読み込み中…