化工社化工社 化学情報印刷レポート · 研究参考用
3-Methyl-5-nitroisoquinoline → 3-Methylisoquinolin-5-amine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-Methyl-5-nitroisoquinoline | HCID 274973 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 3-Methylisoquinolin-5-amine | HCID 12212055 | 76.1% |
反応手順
A solution of (D1) (1 g, 5.3 mM) and 10% palladium on charcoal (0.15 g) in methanol (40 ml) was hydrogenated at atmospheric pressure for 1 h. The catalyst was filtered off and the filtrate concentrated under reduced pressure to afford the product as a grey solid (0.64 g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07528150B2 |
| 出典データセット | uspto-grants-2009_05 |
| ORD ID | ord-75455a89fbf143aba118e50ac228915c |
| 出典メモ | uspto-grants-2009_05 |