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HRID 490989作成日:2026年10月25日

Hydrochloric Acid → Methyl 4-Iodophenylacetate

https://huagongshe.com/reaction/490989

反応式

関与物質

役割名称HCID仕込み量
反応物Hydrochloric AcidHCID 313—
反応物MethanolHCID 887—
反応物4-Iodophenylacetic acidHCID 137214—
溶媒1,4-DioxaneHCID 31275—
生成物Methyl 4-IodophenylacetateHCID 1037870098%

反応手順

To a stirred solution of 4-iodophenylacetic acid (5.0 g, 19.1 mmol) in MeOH (200 mL) was added 4N hydrochloric acid in dioxane (10 mL). The reaction mixture was stirred for 24 h at room temperature and then the solvent was removed under reduced pressure to give the title compound (5.17 g, 98% yield), which was used without further purification.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07528253B2
出典データセットuspto-grants-2009_05
ORD IDord-15ce9d6f095f4c6ebd484d396d6f8dd3
出典メモuspto-grants-2009_05