2-Mercaptoethanol → 2-Isopropenyl-2-oxazoline 2-mercaptoethanol

関与物質

反応手順

2-isopropenyl-2-oxazoline and 2-mercaptoethanol are reacted in toluene at 70° C. A solution of azodiisobutyronitrile (AIBN) in toluene is added to the mixture, and the reaction continued at 70° C. for several hours. The 2-isopropenyl-2-oxazoline/2-mercaptoethanol adduct is obtained after removal of the solvent under reduced pressure. This 2-isopropenyl-2-oxazoline/2-mercaptoethanol adduct is then reacted under nitrogen with maleic anhydride in 300 mL of dimethoxyethane at 70° C. for one hour. After cooling, the contents of the reaction are poured into heptane. The resulting product is dried at 40° C. in vacuo for 24 hours.

情報源と証拠