関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Methyl but-2-ynoate | HCID 141019 | — |
| 反応物 | 2-(Trimethylsiloxy)-1,3-cyclohexadiene | HCID 4095656 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | Methyl 2-methyl-4-trimethylsilyloxybenzoate | HCID 21879730 | 67.1% |
反応手順
A 50 mL round bottom flask equipped with magnetic stir bar and condenser was charged with 6.0 g of 2-trimethylsilyloxy-1,3-cyclohexadiene, 3.5 g methyl tetrolate in 3 mL dry toluene. The reaction was heated to 150° C. for 50 hours at which point 1H-NMR indicated no starting diene. The raction was concentrated in vacuo to provide 5.7 g (67%) methyl 2-methyl-4-trimethylsilyloxybenzoate.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07531538B2 |
|---|
| 出典データセット | uspto-grants-2009_05 |
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| ORD ID | ord-f6711c42874542a784d4e555a169e5ac |
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| 出典メモ | uspto-grants-2009_05 |
|---|
