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1-methyl-1H-indazol-5-amine → 6-(4-Fluorophenyl)-2-methyl-N-(1-methylindazol-5-yl)nicotinamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-methyl-1H-indazol-5-amine | HCID 2768032 | — |
| 反応物 | 6-(4-Fluorophenyl)-2-methylpyridine-3-carboxylic acid | HCID 24277790 | — |
| 生成物 | 6-(4-Fluorophenyl)-2-methyl-N-(1-methylindazol-5-yl)nicotinamide | HCID 10428594 | — |
反応手順
Using the procedure outlined in Example 15, the title compound was prepared from 6-(4-fluorophenyl)nicotinic acid (D3) (100 mg, 0.43 mmol) and 5-amino-1-methylindazole (58 mg, 0.39 mmol) as a white solid (21 mg). MS (ES): MH+ 361, (M−H)− 359.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07531558B2 |
| 出典データセット | uspto-grants-2009_05 |
| ORD ID | ord-6a07dc36a3e74f7db9aea3b362208bca |
| 出典メモ | uspto-grants-2009_05 |