tert-Butyldimethylsilyl chloride → HCID 11387060、化合物
反応式
[Br:1][C:2]1[C:10]2[O:9][C:8]([C:11]3[CH:16]=[CH:15][C:14]([O:17]C)=[CH:13][CH:12]=3)=[N:7][C:6]=2[CH:5]=[C:4]([O:19]C)[CH:3]=1.[C:21]([Si:25](Cl)([CH3:27])[CH3:26])([CH3:24])([CH3:23])[CH3:22]>>[Br:1][C:2]1[C:10]2[O:9][C:8]([C:11]3[CH:12]=[CH:13][C:14]([O:17][Si:25]([C:21]([CH3:24])([CH3:23])[CH3:22])([CH3:27])[CH3:26])=[CH:15][CH:16]=3)=[N:7][C:6]=2[CH:5]=[C:4]([O:19][Si:25]([C:21]([CH3:24])([CH3:23])[CH3:22])([CH3:27])[CH3:26])[CH:3]=1参加物
3
実験手順
The title compound was prepared in substantially the same manner as described in Example 24, Route a, Step a, from 7-bromo-5-methoxy-2-(4-methoxyphenyl)-1,3-benzoxazole, and tertbutyl(chloro)dimethylsilane. The desired product was obtained as a white solid, m.p. 90-91° C.; MS m/e 534 (M+H)+.
後処理
- customThe title compound was prepared in substantially the same manner
出典と根拠
- ORDレコード
- ord-677f684335734f399c72d50fca4faeb5
- 出典データセット
- uspto-grants-2009_05