3-Bromoaniline → (3-Bromophenyl)hydrazine
反応式
[Br:1][C:2]1[CH:3]=[C:4]([NH2:8])[CH:5]=[CH:6][CH:7]=1.[N:9]([O-])=O.[Na+].O.O.Cl[Sn]Cl>Cl>[Br:1][C:2]1[CH:3]=[C:4]([NH:8][NH2:9])[CH:5]=[CH:6][CH:7]=1参加物
5
実験手順
To a solution of 3-bromo-phenylamine (17 g, 0.1 mol) in concentrated HCl (200 mL) was added an aqueous solution (20 mL) of NaNO2 (7 g, 0.1 mol) at 0° C. and the resulting mixture was stirred for 1 h. A solution of SnCl2.2H2O (45 g, 0.2 mmol) in concentrated HCl (500 mL) was then added at 0° C. The reaction solution was stirred for an additional 2 h at RT. The precipitate was filtered and washed with ethanol and ether to give (3-bromo-phenyl)-hydrazine as a white solid, which was used for the next reaction without further purification
後処理
- stirringThe reaction solution was stirred for an additional 2 h at RT
- filtrationThe precipitate was filtered
- washwashed with ethanol and ether
出典と根拠
- ORDレコード
- ord-78b89e00d940413c8a6a14d5c2be8d4b
- 出典データセット
- uspto-grants-2009_05
- 特許番号
- US07531566B2
反応ノート
読み込み中…