Water → Pyrazol-5(4H)-one, 1-(2-benzothiazolyl)-3-methyl-

HRID 493008

反応式

HRID 493008 の反応式
[NH:1]([C:3]1[S:4][C:5]2[CH:11]=[CH:10][CH:9]=[CH:8][C:6]=2[N:7]=1)[NH2:2].[OH2:12]>C(O)(=O)C>[S:4]1[C:5]2[CH:11]=[CH:10][CH:9]=[CH:8][C:6]=2[N:7]=[C:3]1[N:1]1[C:8](=[O:12])[CH2:6][C:5]([CH3:11])=[N:2]1

参加物

4

反応物 2

HCID 962WaterHCID 119882-Benzothiazolinone, hydrazone

生成物 1

HCID 459449Pyrazol-5(4H)-one, 1-(2-benzothiazolyl)-3-methyl-

試薬・触媒・溶媒 1

HCID 176Acetic Acid溶媒

実験手順

2 g (12.1 mmol) of 2-hydrazino-1,3-benzothiazole and 1.58 g (12.1 mmol) of acetoacetic ester are stirred in 40 ml of glacial acetic acid for 2 hours at 90° C. The mixture is then diluted with water and the precipitated crystals are filtered off with suction, washed again with water and dried under reduced pressure.

後処理

  1. filtrationthe precipitated crystals are filtered off with suction
  2. washwashed again with water
  3. customdried under reduced pressure

出典と根拠

ORDレコード
ord-75391b813e274a8b95e1542c76834bcb
出典データセット
uspto-grants-2009_05
特許番号
US07534273B2

関連ノート

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