関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 2-(2-Naphthoxy)ethanol | HCID 7131 | — |
| 反応物 | Sodium hydride | HCID 24758 | — |
| 反応物 | 2,3-Dichloropyrazine | HCID 78575 | — |
| 溶媒 | 1,4-Dioxane | HCID 31275 | — |
| 生成物 | 2-Chloro-3-[2-(2-naphthyloxy)ethoxy]pyrazine | HCID 23509565 | — |
反応手順
Sodium hydride (55% dispersion in mineral oil; 44 mg, 1.0 mmol) was added to a mixture of 2-(2-naphthoxy)ethanol (188 mg, 1.00 mmol) and 2,3-dichloropyrazine (149 mg, 1.00 mmol) in dioxane (0.5 mL), and the reaction mixture was stirred at 40° C. for 15 h. The crude material was used directly in Step 2.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07534794B2 |
|---|
| 出典データセット | uspto-grants-2009_05 |
|---|
| ORD ID | ord-bfed6779a35d4e33a019655fe10f3cc9 |
|---|
| 出典メモ | uspto-grants-2009_05 |
|---|
