化工社化工社 化学情報印刷レポート · 研究参考用
Acetamide → N-Acetyl-1,6-diaminohexane
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetamide | HCID 178 | — |
| 反応物 | Hexamethylenediamine | HCID 16402 | — |
| 生成物 | N-Acetyl-1,6-diaminohexane | HCID 162081 | — |
反応手順
Hexamethylenediamine (90.64 g; 0.6 mol) and acetamide (11.81 g; 0.2 Mol) were stirred and refluxed for 10 hours under nitrogen. The solution was cooled overnight and then distilled under vacuum <100° C. as fast as possible. The N-acetylhexylenediamine was then separated from the resultant mixture by flash chromatography [SiO2/EtOH:25%aq.NH3 (4:1)]. The title product was obtained as a white crystalline product (18.43 g; 58% theory).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06706855B1 |
| 出典データセット | uspto-grants-2004_03 |
| ORD ID | ord-35c5df770b194cc5a9ffc293550b73f2 |
| 出典メモ | uspto-grants-2004_03 |