Hydroxylamine → N-(3,4-dihydro-2H-naphthalen-1-ylidene)hydroxylamine
反応式
[C:1]1(=O)[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][CH2:2]1.[NH2:12][OH:13]>C(O)C.O>[C:1]1(=[N:12][OH:13])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][CH2:2]1参加物
5
実験手順
To a solution of 5 mL (37.5 mmole) 1-tetralone in 25 mL ethanol was added 2.7 mL (40 mmole) of 50% hydroxylamine in water. The reaction mixture was heated under reflux for 2 hrs, then stirred at room temperature for 16 hrs. The solution was concentrated under reduced pressure. The residue was recrystallized from toluene/hexane to give 1-tetralone oxime (3,4-dihydro-2H-naphthalen-1-one oxime), 3.86 g, m.p. 101-102°.
後処理
- temperatureThe reaction mixture was heated
- temperatureunder reflux for 2 hrs
- concentrationThe solution was concentrated under reduced pressure
- customThe residue was recrystallized from toluene/hexane
出典と根拠
- ORDレコード
- ord-2acf8498a3144385b07360a027384d7e
- 出典データセット
- uspto-grants-2005_09
- 特許番号
- US06943169B2
反応ノート
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