化工社化工社 化学情報印刷レポート · 研究参考用
Ethyl diazoacetate → Ethyl 2-(benzyloxymethyl)cyclopropanecarboxylate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethyl diazoacetate | HCID 12192 | — |
| 反応物 | Allyl benzyl ether | HCID 84542 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 生成物 | Ethyl 2-(benzyloxymethyl)cyclopropanecarboxylate | HCID 22325150 | — |
反応手順
31.2 g of ethyl diazoacetate are added to a solution of 0.3 mol of allyl benzyl ether in 150 ml of ether with the aid of a push-syringe. After stirring for 16 hours, 31.2 g of ethyl diazoacetate are added again. After 24 hours the mixture is filtered. The organic phase is washed with saturated NaHCO3 solution and then treated in customary manner. Chromatography over silica gel (dichloromethane) allows the expected product to be obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06943184B2 |
| 出典データセット | uspto-grants-2005_09 |
| ORD ID | ord-c809cba580fc45cd9cee4bfaa41681aa |
| 出典メモ | uspto-grants-2005_09 |