Magnesium → HCID 22324841、化合物
反応式
CO[C:3]1[C:8]([O:9][CH3:10])=[CH:7][CH:6]=[CH:5][C:4]=1[C:11]1[O:12]CC(C)(C)N=1.Br[CH2:19][CH2:20][C:21]1[CH:25]=[CH:24][S:23][CH:22]=1.[Mg]>>[CH3:10][O:9][C:8]1[C:3]([CH2:19][CH2:20][C:21]2[CH:25]=[CH:24][S:23][CH:22]=2)=[C:4]([CH2:11][OH:12])[CH:5]=[CH:6][CH:7]=1参加物
4
実験手順
Using the method of example 44, steps 1-3, with 2-(2,3-dimethoxyphenyl)-4,4-dimethyl-2-oxazoline (J. Org. Chem. 43, 1372 (1978) and the Grignard reagent prepared from 1-bromo-2-(3-thiophenyl)ethane and magnesium the title compound was prepared and the structure confirmed by NMR spectroscopy. 4. 3-[2-(2-Bromomethyl-6-methoxy-phenyl)-ethyl]-thiophene
出典と根拠
- ORDレコード
- ord-706adb0dae9c4425911b21dceca1ad7f
- 出典データセット
- uspto-grants-2005_09
- 特許番号
- US06943183B2
反応ノート
読み込み中…