Silicon tetrachloride → 3-Cyano-2,4,5-trifluoro-benzoyl chloride
反応式
[C:1]([C:3]1[C:4]([F:14])=[C:5]([CH:9]=[C:10]([F:13])[C:11]=1[F:12])[C:6](F)=[O:7])#[N:2].[Cl-].[Al+3].[Cl-].[Cl-].[Si](Cl)(Cl)(Cl)[Cl:20]>>[C:1]([C:3]1[C:4]([F:14])=[C:5]([CH:9]=[C:10]([F:13])[C:11]=1[F:12])[C:6]([Cl:20])=[O:7])#[N:2]参加物
4
実験手順
76.6 g of 3-cyano-2,4,5-trifluoro-benzoyl fluoride were initially introduced together with 1 g of anhydrous aluminium chloride at 60-65° C., and 25 g of silicon tetrachloride were then added dropwise at the rate of gas evolution. After the evolution of gas at 65° C. had ceased, the mixture was distilled under reduced pressure. In the boiling range from 120-122° C./14 mbar, 73.2 g of 3-cyano-2,4,5-trifluoro-benzoyl chloride passed over.
後処理
- customat 65° C.
- distillationthe mixture was distilled under reduced pressure
- customfrom 120-122° C.
出典と根拠
- ORDレコード
- ord-2a315c50a0324e4db11b5cd2776cefc3
- 出典データセット
- uspto-grants-2004_03
- 特許番号
- US06706918B2
反応ノート
読み込み中…