Nitromethane → HCID 53659307、化合物

反応式

[CH2:1]([O:8][C:9](=[O:16])[CH2:10][CH2:11][Si:12](Cl)([Cl:14])[Cl:13])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[N+:17]([CH3:20])([O-:19])=[O:18].C(N(CC)CC)C>>[CH2:1]([O:8][C:9](=[O:16])[CH2:10][CH2:11][Si:12]([Cl:14])([Cl:13])[CH2:20][N+:17]([O-:19])=[O:18])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

参加物

反応物 3

HCID 6375Nitromethane

HCID 8471Triethylamine

HCID 541048793-(Trichlorosilyl) Propionic Acid Benzyl Ester

生成物 1

HCID 53659307HCID 53659307、化合物

反応条件

温度: 0 °C

実験手順

298 g (1 mole) of 3-(trichlorosilyl) propionic acid benzyl ester (I) is dissolved in 540 ml (10 mol) of nitromethane and cooled to 0° C. Added dropwise 139 ml (1 mol) of triethylamine over a period of 2 hours. The mixture is then distilled through a 22 mm×4 ft. Podbielniak column packed with Heli-pak to give 3-(dichloronitromethylsilyl) propionic acid benzyl ester (II).