化工社化工社 化学情報印刷レポート · 研究参考用
Diethyl (ethoxymethylene)malonate → Diethyl {[(1-phenyl-5-pyrazolyl)amino]methylene}malonate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Diethyl (ethoxymethylene)malonate | HCID 6871 | — |
| 反応物 | 1-Phenylpyrazol-5-ylamine | HCID 70006 | — |
| 生成物 | Diethyl {[(1-phenyl-5-pyrazolyl)amino]methylene}malonate | HCID 22322171 | — |
反応手順
A mixture of 15.9 g. (0.10 mole) of 1-phenyl-5-aminopyrazole and 21.6 g. (0.10 mole) of diethyl ethoxymethylenemalonate was heated at 115-120° in an oil bath for 2 hours. After cooling, the crystalline mass was recrystallized from hot hexane containing 1% of ethanol. Cooling to room temperature and filtering gave 24.8 g. (75%) of off-white crystals, m.p. 96-97° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06946473B2 |
| 出典データセット | uspto-grants-2005_09 |
| ORD ID | ord-60679c5493b845128f880a7f14bce9ac |
| 出典メモ | uspto-grants-2005_09 |