Ammonia → 5-Amino-3,4-dihydronaphthalen-1(2H)-one
反応式
S(=O)(=O)(O)[OH:2].N[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[CH2:13][CH2:14][CH2:15][C:16]#[N:17].N>>[NH2:17][C:16]1[CH:15]=[CH:14][CH:13]=[C:8]2[C:9]=1[CH2:10][CH2:11][CH2:12][C:7]2=[O:2]参加物
4
反応条件
- 温度
- 100 °C
実験手順
In a 20 ml Schlenk vessel, 1 g of 96% sulfuric acid (9.79 mmol) is added to 100 mg of 4-(2-aminophenyl)butyronitrile (0.62 mmol) under argon. The mixture is heated to 100° C. for 66 h, stirring. After cooling, it is neutralised with aqueous ammonia solution (ice cooling), and the product is then extracted with chloroform and identified using GC.
後処理
- temperatureAfter cooling
- extractionthe product is then extracted with chloroform
出典と根拠
- ORDレコード
- ord-a8a01279e9524fbab2b2b0eb6ff5f636
- 出典データセット
- uspto-grants-2004_03
- 特許番号
- US06706924B2
反応ノート
読み込み中…