Hydrochloric Acid → 5-Acetyl-2-methoxybenzoic acid
反応式
[CH3:1][O:2][C:3]1[CH:12]=[CH:11][C:10]([C:13](=[O:15])[CH3:14])=[CH:9][C:4]=1[C:5]([O:7]C)=[O:6].Cl>C(O)(=O)C>[CH3:1][O:2][C:3]1[CH:12]=[CH:11][C:10]([C:13](=[O:15])[CH3:14])=[CH:9][C:4]=1[C:5]([OH:7])=[O:6]参加物
4
実験手順
Methyl 2-methoxy-5-acetylbenzoate (Step A, 3 g, 14.4 mmol) was dissolved in acetic acid (80 ml) and then treated with c HCl (28 ml). The reaction mixture was refluxed for 4 hours, concentrated under reduced pressure and lyophilized to provide the title compound as cream color solid, which was used without further purification.
後処理
- temperatureThe reaction mixture was refluxed for 4 hours
- concentrationconcentrated under reduced pressure
出典と根拠
- ORDレコード
- ord-0863c216b3f74a7ab23aea09429c1f3c
- 出典データセット
- uspto-grants-2005_09
- 特許番号
- US06946491B2
反応ノート
読み込み中…