N,N'-bis-(2-amino-ethyl)-N,N'-dimethyl-propane-1,3-diamine → 3-chloro-6-{2-[(3-{[2-(3-chloro-7-oxo-7H-5,9-diaza-benzo[c]fluoren-6-ylamino)-ethyl]-methyl-amino}-propyl)-methyl-amino]-ethylamino}-5,9-diaza-benzo[c]fluoren-7-one
反応式
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[C:17]3[C:16]4[CH:15]=[CH:14][N:13]=[CH:12][C:11]=4[C:10](=[O:18])[C:9]=3[C:8](CS(C3C=CC(C)=CC=3)(=O)=O)=[N:7][C:6]=2[CH:30]=1.[NH2:31][CH2:32][CH2:33][N:34]([CH3:43])[CH2:35][CH2:36][CH2:37][N:38]([CH2:40][CH2:41][NH2:42])[CH3:39]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[C:17]3[C:16]4[CH:15]=[CH:14][N:13]=[CH:12][C:11]=4[C:10](=[O:18])[C:9]=3[C:8]([NH:42][CH2:41][CH2:40][N:38]([CH2:37][CH2:36][CH2:35][N:34]([CH2:33][CH2:32][NH:31][C:8]3[C:9]4[C:10](=[O:18])[C:11]5[CH:12]=[N:13][CH:14]=[CH:15][C:16]=5[C:17]=4[C:5]4[CH:4]=[CH:3][C:2]([Cl:1])=[CH:30][C:6]=4[N:7]=3)[CH3:43])[CH3:39])=[N:7][C:6]=2[CH:30]=1参加物
3
反応物 2
生成物 1
実験手順
In a similar manner to Example 4, this compound was obtained starting from 3-chloro-6-(toluene-4-sulfonylmethyl)-5,9-diaza-benzo[c]fluoren-7-one (the compound of Reference Example 7c-2) and N,N′-bis-(2-amino-ethyl)-N,N′-dimethyl-propane-1,3-diamine. The desired product was obtained as a reddish powder.