Triethylamine → tert-Butyl 3-aminopropanoate

HRID 497007ノート

反応式

HRID 497007 の反応式
Cl.[C:2]([O:6][C:7](=[O:11])[CH2:8][CH2:9][NH2:10])([CH3:5])([CH3:4])[CH3:3].C(N(CC)CC)C>C(Cl)Cl>[C:2]([O:6][C:7](=[O:11])[CH2:8][CH2:9][NH2:10])([CH3:5])([CH3:4])[CH3:3]

参加物

4

反応物 2

HCID 8471TriethylamineHCID 16218890Tert-butyl 3-aminopropanoate hydrochloride

生成物 1

HCID 4192171tert-Butyl 3-aminopropanoate

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

To a solution of β-alanine t-butyl ester hydrochloride (5 mmol, SIGMA) in CH2Cl2 (20 mL) was added triethylamine (5 mmol) at RT After the solution was stirred at RT for 15 mins, the precipitate formed was filtered and the CH2Cl2 was removed in vacuo to give the free amine, β-alanine t-butyl ester.

後処理

  1. customthe precipitate formed
  2. filtrationwas filtered
  3. customthe CH2Cl2 was removed in vacuo

出典と根拠

ORDレコード
ord-0b961f3abcdd4277846e8487a30e5a18
出典データセット
uspto-grants-2005_09
特許番号
US06949534B2

反応ノート

読み込み中…