1-(7-Methoxy-benzo[1,3]dioxol-5-yl)-ethanol → Acetophenone, 5-methoxy-3,4-methylenedioxy-
反応式
[CH3:1][O:2][C:3]1[C:8]2[O:9][CH2:10][O:11][C:7]=2[CH:6]=[C:5]([CH:12]([OH:14])[CH3:13])[CH:4]=1>ClCCl.[O-2].[O-2].[Mn+4]>[CH3:1][O:2][C:3]1[C:8]2[O:9][CH2:10][O:11][C:7]=2[CH:6]=[C:5]([C:12](=[O:14])[CH3:13])[CH:4]=1参加物
4
実験手順
Manganese dioxide (5 g, molar excess) was added to a solution of 2 (0.89 g, 4.5 mmol) in dichloromethane (10 mL). The resulting mixture was heated at reflux for 3 hours then filtered through Celite®. The filtrate was concentrated in vacuo to afford 3 as a tan solid.
後処理
- temperatureThe resulting mixture was heated
- temperatureat reflux for 3 hours
- filtrationthen filtered through Celite®
- concentrationThe filtrate was concentrated in vacuo
出典と根拠
- ORDレコード
- ord-4e74b31245e842a5a30e269e722fa707
- 出典データセット
- uspto-grants-2005_09
- 特許番号
- US06949544B2
反応ノート
読み込み中…