Hydrochloric Acid → (RS) 3-(6-amino-pyrid-3-yl)-butanoic acid hydrochloride
反応式
C([NH:4][C:5]1[N:10]=[CH:9][C:8]([CH:11]([CH3:18])[CH2:12][C:13]([O:15]CC)=[O:14])=[CH:7][CH:6]=1)(=O)C.[ClH:19]>>[ClH:19].[NH2:4][C:5]1[N:10]=[CH:9][C:8]([CH:11]([CH3:18])[CH2:12][C:13]([OH:15])=[O:14])=[CH:7][CH:6]=1参加物
3
実験手順
A solution of (RS) ethyl 3-(6-acetylamino-pyrid-3-yl)-butanoate (25.56 g, Reference Example 21) in aqueous hydrochloric acid (500 mL, 6M) was heated at 100° C. for 3.5 hours, then cooled and then evaporated to give the title compound as a crystalline solid.
後処理
- temperaturecooled
- customevaporated
出典と根拠
- ORDレコード
- ord-6982c1d35e444c62b2ca924c5617f84e
- 出典データセット
- uspto-grants-2004_03
- 特許番号
- US06706738B2
反応ノート
読み込み中…