Sulfanilamide → 4-sulfamoyl-N-[4-(2-furyl)benzylidene]aniline

HRID 497192ノート

反応式

HRID 497192 の反応式
[CH:1]([C:3]1[CH:8]=[CH:7][C:6]([C:9]2[O:10][CH:11]=[CH:12][CH:13]=2)=[CH:5][CH:4]=1)=O.[S:14]([NH2:24])(=[O:23])([C:16]1[CH:21]=[CH:20][C:19]([NH2:22])=[CH:18][CH:17]=1)=[O:15]>C(O)C>[S:14]([C:16]1[CH:21]=[CH:20][C:19]([N:22]=[CH:1][C:3]2[CH:8]=[CH:7][C:6]([C:9]3[O:10][CH:11]=[CH:12][CH:13]=3)=[CH:5][CH:4]=2)=[CH:18][CH:17]=1)(=[O:15])(=[O:23])[NH2:24]

参加物

4

反応物 2

HCID 5333SulfanilamideHCID 27722954-(Furan-2-yl)benzaldehyde

生成物 1

HCID 223167314-sulfamoyl-N-[4-(2-furyl)benzylidene]aniline

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

A mixture of 2-(4-formylphenyl)furan (0.335 g, 1.95 mmol, prepared according to the method of Heterocycles, 1990, 31, 1951), sulfanilamide (0.336 g, 1.95 mmol) in ethanol (8 mL) was heated at reflux temperature for 2.5 hour. After cooling to room temperature, the crystals which collected by filtration and washed with ethanol to give the subtitle compound (0.378 g).

後処理

  1. customprepared
  2. temperaturewas heated
  3. temperatureat reflux temperature for 2.5 hour
  4. filtrationthe crystals which collected by filtration
  5. washwashed with ethanol

出典と根拠

ORDレコード
ord-5208b50a82624ff28da19943635fcb99
出典データセット
uspto-grants-2005_09
特許番号
US06949536B2

反応ノート

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