化工社化工社 化学情報印刷レポート · 研究参考用
Potassium Carbonate → [4-(1,4-Benzodioxan-5-yl)-1,2,3,6-tetrahydropyrid-1-yl]acetonitrile
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | Bromoacetonitrile | HCID 11534 | — |
| 反応物 | 4-[(1,4-Benzodioxan-5-yl)]-1,2,3,6-tetrahydropyridine hydrochloride | HCID 19096238 | — |
| 溶媒 | Acetone | HCID 180 | — |
| 生成物 | [4-(1,4-Benzodioxan-5-yl)-1,2,3,6-tetrahydropyrid-1-yl]acetonitrile | HCID 19105274 | — |
反応手順
2.5 g of potassium carbonate and, dropwise, a solution of 1.08 g of bromoacetonitrile in 10 ml of acetone are added to a solution of 1.9 g of the amine hydrochloride obtained in Stage B in 40 ml of acetone.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05242933 |
| 出典データセット | uspto-grants-1993_09 |
| ORD ID | ord-8836235aef454333bcb8b379cc7831d3 |
| 出典メモ | uspto-grants-1993_09 |