3-(4-Bromophenyl)4-(3-fluoro-4-methylthiophenyl)-5-methyl-4,5-dihydro-5-isoxazolol → 4-(4-Bromophenyl)-3-(4-methylthiophenyl)-5-methylisoxazole

HRID 497293ノート

反応式

HRID 497293 の反応式
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]2[C:12]([CH3:14])(O)[O:11][N:10]=[C:9]2[C:15]2[CH:20]=[CH:19][C:18]([S:21][CH3:22])=[CH:17][CH:16]=2)=[CH:4][CH:3]=1.BrC1C=CC(C2C(C3C=CC(SC)=C(F)C=3)C(C)(O)ON=2)=CC=1>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:9]([C:15]3[CH:20]=[CH:19][C:18]([S:21][CH3:22])=[CH:17][CH:16]=3)=[N:10][O:11][C:12]=2[CH3:14])=[CH:4][CH:3]=1

参加物

3

反応物 2

HCID 227239503-(4-Bromophenyl)4-(3-fluoro-4-methylthiophenyl)-5-methyl-4,5-dihydro-5-isoxazololHCID 543484634-(4-Bromophenyl)-3-(4-methylthiophenyl)-5-methyl-4,5-dihydro-5-isoxazolol

生成物 1

HCID 542865314-(4-Bromophenyl)-3-(4-methylthiophenyl)-5-methylisoxazole

実験手順

The title compound was prepared according to the procedure of step 2 in the Example 168 using 4-(4-bromophenyl)-3-(4-methylthiophenyl)-5-methyl-4,5-dihydro-5-isoxazolol, instead of 3-(4-bromophenyl)-4-(3-fluoro-4-methylthiophenyl)-5-methyl-4,5-dihydro-5-isoxazolol.

出典と根拠

ORDレコード
ord-dff38b00360c4c158d75c22bfa203dcd
出典データセット
uspto-grants-2005_09
特許番号
US06949536B2

反応ノート

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