Stannous chloride dihydrate → Carbamic acid,[2-amino-5-ethenyl-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl ester

HRID 498221

反応式

HRID 498221 の反応式
[C:1]([O:5][C:6](=[O:23])[NH:7][C:8]1[CH:13]=[C:12]([CH:14]=[CH2:15])[C:11]([C:16]([F:19])([F:18])[F:17])=[CH:10][C:9]=1[N+:20]([O-])=O)([CH3:4])([CH3:3])[CH3:2].O.O.Cl[Sn]Cl>>[C:1]([O:5][C:6](=[O:23])[NH:7][C:8]1[CH:13]=[C:12]([CH:14]=[CH2:15])[C:11]([C:16]([F:19])([F:18])[F:17])=[CH:10][C:9]=1[NH2:20])([CH3:2])([CH3:3])[CH3:4]

参加物

3

反応物 2

HCID 61436Stannous chloride dihydrateHCID 69486631(2-Nitro-4-trifluoromethyl-5-vinyl-phenyl)-carbamic acid tert-butyl ester

生成物 1

HCID 69486994Carbamic acid,[2-amino-5-ethenyl-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl ester

実験手順

The title compound was prepared from (2-nitro-4-trifluoromethyl-5-vinyl-phenyl)-carbamic acid tert-butyl ester (Example A27) (1.01 g, 3.0 mmol) by reduction with SnCl2.2H2O according to the general procedure J (method b). Obtained as an orange solid (669 mg, 74%).

出典と根拠

ORDレコード
ord-92ed79ca26d0425bad58605b8fed4e2b
出典データセット
uspto-grants-2005_09
特許番号
US06949542B2

関連ノート

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