CO[C:3](=[O:17])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([C:10]2[CH:15]=[CH:14][N:13]=[C:12]([CH3:16])[N:11]=2)[CH:5]=1.[C:18]([C:21]1[CH:22]=C(C=C[CH:29]=1)C(O)=O)(=O)C.C(NC(N[C:40](=[O:42])[CH3:41])NC(=O)C)(=O)C.[OH:43]S(O)(=O)=O>O>[C:21]([O:43][C:40](=[O:42])[CH2:41][C:3]([C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([C:10]2[CH:15]=[CH:14][N:13]=[C:12]([CH3:16])[N:11]=2)[CH:5]=1)=[O:17])([CH3:22])([CH3:29])[CH3:18]The title compound was prepared from 3-(2-methyl-pyrimidin-4-yl)-benzoic acid methyl ester [prepared by the following procedure: A mixture of 3-acetyl-benzoic acid (0.82 g, 5 mmol), N-(bis-acetylamino-methyl)-acetamide (0.94 g, 5 mmol) and conc. H2SO4 (0.01 ml) was heated to 155° C. for 6 h. The cooled mixture was diluted with H2O (20 ml) and the precipitate was collected, dried and esterified by heating in MeOH (12 ml)/4N HCl-Et2O (3 ml) for 20 h at 40° C.; white crystals (0.27 g).] (0.80 g, 3.5 mmol by treatment with lithium tert-butyl acetate according to general procedure K (method b). Obtained as a yellow solid (1.36 g, crude product).
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