化工社化工社 化学情報印刷レポート · 研究参考用
L-Leucine, N-((1,1-dimethylethoxy)carbonyl)- → Boc-Leu-Gly-Leu-Ala-OBzl
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | L-Leucine, N-((1,1-dimethylethoxy)carbonyl)- | HCID 83170 | — |
| 反応物 | H-Gly-Leu-Ala-OBzl | HCID 131717745 | — |
| 生成物 | Boc-Leu-Gly-Leu-Ala-OBzl | HCID 131717746 | — |
反応手順
Boc-Leu-Gly-Leu-Ala-OBzl was prepared by coupling Boc-Leu-OH (2.62 g, 10.5 mmoles) to H-Gly-Leu-Ala-OBzl using the mixed anhydride procedure described in Example 2. The resulting product was crystallized from ethyl acetate:hexane to yield 2.7 g (mp 95°-96°) in the first crop.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05242904 |
| 出典データセット | uspto-grants-1993_09 |
| ORD ID | ord-dcb3efb5c2714b649c6024418e3d449a |
| 出典メモ | uspto-grants-1993_09 |