関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | 1,4-Dioxane | HCID 31275 | — |
| 反応物 | 6-Quinolinecarboxylic acid | HCID 82571 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 6-Quinolinecarboxylic acid, ethyl ester | HCID 94670 | — |
反応手順
4.9 g of quinoline-6-carboxylic acid was stirred in 80 ml of ethanol. 40 ml of dioxane containing 4 M of hydrogen chloride was added to the obtained mixture. After stirring at 70° C. overnight, the solvent was evaporated and the residue was treated with ethyl acetate as the extracting solvent by an ordinary method to obtain the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US06710056B2 |
|---|
| 出典データセット | uspto-grants-2004_03 |
|---|
| ORD ID | ord-39bdd5917a824cf489af4d15fa464529 |
|---|
| 出典メモ | uspto-grants-2004_03 |
|---|
