2-Mercaptoethanol → 5-[2-[(2-hydroxyethyl)thio]-2-(3-thienyl)ethyl]-2-methyl-2-phenylfuran-3(2H)-one

関与物質

反応手順

Following the procedure of Method C, Example 1, (E)-2-methyl-2-phenyl-5-[2-(3-thienyl)ethenyl]-3(2H)-furanone was reacted with 2-mercapto-1-ethanol to provide 5-[2-[(2-hydroxyethyl)thio]-2-(3-thienyl)ethyl]-2-methyl-2-phenylfuran-3(2H)-one: 1H NMR (DMSO-d6) δ1.54 and 1.57 (singlets, 3H), 3.35-3.60 (m ovelapped with DMSO, ˜4H), 4.58 (m, 1H), 5.55 and 5.56 (overlapped singlets, 1H), 7.18-7.37 (m, 6H), 7.40-7.57 (m, 2H); MS(LR-ESI) m/z 361 (M+H calcd. for C19H21O3S2 361).

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